“Paraquat increases the production of certain derivatives of oxygen that can damage cellular structures,” he added. “People who have used these pesticides or other by the same mechanism of action were more likely to develop Parkinson’s disease.”The two pesticides are not approved for use in home or garden, in the United States. paraquat use is limited to certified applicators and only approved use rotenone to kill the invasive fish, according to the press release.
The study was recently published online in the journal Environmental Health Perspectives.
“Rotenone inhibits mitochondrial function directly, the structure responsible for making energy in the cell,” study co-author Freya Kamel, a researcher at the National Institute of Environmental Health Sciences, said in a press release by the Institute.
U.S. researchers compared 110 people with Parkinson’s disease and 358 people without the disorder of the nervous system. All participants were enrolled in agriculture and Movement Evaluation Study involving pesticide applicators and their spouses allowed.
Thursday, February 17 – People who use pesticides rotenone and paraquat were 2.5 times more likely to develop Parkinson’s disease, a new study.
“These results help us understand the biological changes underlying Parkinson’s disease. This may have important implications for treatment and ultimately prevention of Parkinson’s disease,” the author Dr. Caroline Tanner, director of the Clinical Research Institute of Parkinson’s Disease and Clinical Center in Sunnyvale, Calif., said in a press release.