Scientists discover new link to the nerve cell loading Hitch Motors

In addition to his work on the mechanisms of cellular transport, Langford is looking for ways to produce more effective drugs for the treatment of Candida albicans, a fungus that causes infections in humans.By understanding how the process works in normal cells, it is possible for scientists to find ways to put out a malfunction of the transport system, Langford said. For example, over-production of dopamine, a neurotransmitter has been linked to depression and other mental illnesses. Also prevent the transport of neurotransmitter-contracting muscle can relieve painful muscle spasms associated with Parkinson’s disease and severe damage to the nervous system.

The transport of neurotransmitter vesicles of the synapse is essential for the function of nerve cells, Langford said. We want to understand all the molecular components involved in the transport process. We have discovered another hiccup that connects the engine at full load.

The study, published in the April 22 issue of the Journal of Biological Chemistry , describes the discovery of a protein that is involved in the mechanism of motor freight neurotransmitter chemical synapses of nerve cells. The synapse is the junction where signals are electrical and chemical signals from one nerve cell to another cell. JBC is the first magazine of the American Society for Biochemistry and Molecular Biology.

The discovery was made by a team of scientists led by George M. The research team included associate and assistant professor Torsten Wollert Michael Cosgrove in the biology department, and the staff of Dartmouth College, the Marine Biological Laboratory in Woods Hole, and the McLaughlin Research Institute. The study was funded by the National Institutes of Health.

The device has the ability to detect other molecules indicative of other diseases, Course WebMD. You can also monitor the effectiveness of certain treatments, or be used as an inexpensive home test for cancer patients to use to see if their cancer has returned after treatment.

Langford’s research has been devoted to understanding how to move organelles within cells. It ‘was the first to observe the movement of synaptic vesicles to actin filaments, in addition to their already well-known transport on microtubules in nerve cells.

Actin filaments and microtubules are the roads on which molecular motors transport their cargo.

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