Revisited Human Relations worm shed light on Brain Evolution

‘We must be able to interpret the molecular events in the medical field,’ he said. ‘And ‘what is happening in different lineages of neurons, for example, completely new, or is it something that is reflected in the tables ancestral instruments preserved over 550 million years of our evolutionary history? Working with models of human diseases, you really need to be sure. ‘‘The man is nothing but a worm’ was the title of a famous caricature of Darwin’s ideas in Victorian England. Now, 120 years later, molecular analysis of mysterious marine creatures unexpectedly reveals our cousins, such as worms, indeed.

‘The rapid development of guidelines for vertebrates, starfish and acorn worms is much more complex than people expect, because it involves not only gain the gene, but the loss of the gene enormous,’ said Mr. Moroz, who is affiliated with the Laboratory for Marine Biosciences Whitney McKnight Brain Institute and UF. ‘An alternative, yet unlikely, scenario would be that our common ancestor had a central nervous system, and only then lost, while remaining a free living organism.

An international team of researchers, including a neuroscientist at the University of Florida, has produced further evidence that people have a close relationship with the evolution of small flatworm-like organisms scientifically known as ‘Acoelomorphs’.

‘It ‘was like looking under a rock and find something unexpected,’ said Leonid L. Moroz, Ph.D., professor of neuroscience with the Faculty ‘of Medicine, UF. ‘We knew it was very unusual twists in the evolution of complex brain, but suggests the independent evolution of complex brains in our lineage from invertebrates, for example, guidelines for octopus or the ‘Bee.’

‘If you look at one of these creatures would have to say:’ What is all this enthusiasm for a worm? ‘Said Richard G. Northcutt, Ph.D., professor of neuroscience at the Scripps Institution of Oceanography, who was not involved in the study.’ These are very small animals that have almost no anatomy, which has few scientists compare them with those, but thanks to genetics, if the analysis is correct -. And time will tell if it is – the study group has taken a very disturbing that scientists are not sure what to do with and say that is related to vertebrates, ourselves and echinoderms (such as starfish).

The research (February 10) Thursday issue of Nature provides an overview of brain development and human diseases, may shed light on the animal models used to study the development of nerve cells and complex neurodegenerative diseases like Alzheimer’s and Parkinson’s.

By comparing large genome-wide data, mitochondrial genes and signaling small nucleic acids called microRNAs, researchers from six countries has created a strong possibility that acoels and their parents are ‘sisters’ to another particular type of marine worm of the North Sea, Xenoturbella called.

The scientists used high-throughput computational tools to reconstruct deep evolutionary relationships, which seems to confirm suspicions that the three lines of marine worms and vertebrates are part of a common evolutionary line called ‘deuterostomes’ who share a common ancestor.

Understanding the complex cellular rearrangements and the origin of animal innovations, such as the brain, it is extremely important for understanding human development and disease, said Mr.

Moroz.

This entry was posted in gear. Bookmark the permalink.

Comments are closed.